Treatment of osteonecrosis of the femoral head using autologous cultured osteoblasts: a case report
نویسندگان
چکیده
INTRODUCTION Osteonecrosis of the femoral head is a progressive disease that leads to femoral head collapse and osteoarthritis. Our goal in treating osteonecrosis is to preserve, not to replace, the femoral head. CASE PRESENTATION We present the case of a patient with bilateral osteonecrosis of the femoral head treated with autologous cultured osteoblast injection. CONCLUSION Although our experience is limited to one patient, autologous cultured osteoblast transplantation appears to be effective for treating the osteonecrosis of femoral head.
منابع مشابه
Femoral Head Avascular Necrosis in Heterozygous Sickle Haemoglobin, the Role of Parenteral Drug Abuse: A Case Report
Sickle cell trait is a benign haemoglobin disorder which rarely results in disease or complications. A few cases of osteonecrosis have been reported in the literature in parts of the world with advanced health care system. There are various predispositions to developing avascular necrosis in general, while the sickle beta globin gene inheritance is the most efficient factor. Injection drug abus...
متن کاملThe Fate and Distribution of Autologous Bone Marrow Mesenchymal Stem Cells with Intra-Arterial Infusion in Osteonecrosis of the Femoral Head in Dogs
This study aimed to investigate if autologous bone marrow mesenchymal stem cells (MSCs) could treat osteonecrosis of the femoral head (ONFH) and what the fate and distribution of the cells are in dogs. Twelve Beagle dogs were randomly divided into two groups: MSCs group and SHAM operated group. After three weeks, dogs in MSCs group and SHAM operated group were intra-arterially injected with aut...
متن کاملTreatment of Femoral Head Osteonecrosis (Stages 2B, 3 Ficat) Through Open Direct Core Decompression by Allograft Impaction and Light Bulb Technique
Background: Femoral head avascular necrosis is the cause of paralyzing status of youth population. Initial diagnosisis the main element in treating the disease. Bone grafting and core decompression are the approved cures at the earlysteps of the disease. Hip replacement in a total manner is the common cure in the final stages. The optimal treatment inthe intermediate stages is...
متن کاملNot-Approved Weight Gain Supplements as a Cause of AVN: A Cautionary Report
Introduction: Avascular necrosis (AVN) of the femoral head is a leading cause of end-stage joint disease in the young population that can conduct patients to total hip replacement in early life. There are various risk factors including, trauma, corticosteroids, thrombosis, hypertension, and alcohol. There is a growing number of femoral head AVN patients with a history of self-medication with he...
متن کاملAvailable Findings Fail to Provide Strong Evidence of the Role of Bone Morphogenic Protein-2 in Femoral Head Osteonecrosis
Despite widespread research on non-traumatic femoral head osteonecrosis (FHON), there is no consensus about preventative treatment options. Insufficient blood supply and increased intra-osseous pressure are the initiating events in the majority of cases. BMPs are growth factors that belong to the transforming growth factor β (TGFβ) superfamily. Two specific formulations of BMPs have already bee...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of Medical Case Reports
دوره 2 شماره
صفحات -
تاریخ انتشار 2008